Abnormal blood stem cells reprogram their environment

Blood arises from stem cells in the bone marrow; in patients with a myelodysplastic disorder (MDS), defective stem cells reprogram their neighbors in the marrow to create a “niche” that promotes their own survival. A recent report by scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in collaboration with colleagues from the University Medical Centre Mannheim, suggests that …

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