HO-1 makes obese individuals sick
Study unravels a link between obesity and diabetes and suggests promising therapeutic strategies. Health and obesity are not mutually exclusive. Freiburg and Vienna scientists identify one key difference separating individuals with healthy versus sick obesity: the enzyme heme oxygenase-1 (HO-1). Humans and mice with high HO-1 levels develop diabetes, those with low levels remain healthy – even when overweight. The …